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 Describe the structure of the blood-brain barrier and explain why it is important.

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Tightly joined endothelial cells form th...

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 Dalton has been diagnosed with Korsakoff's syndrome. What likely caused his disorder?


A) He is an alcoholic and has damaged his nervous system such that glucose cannot cross the blood-brain barrier.
B) He has been exposed to a virus that has now started killing neurons.
C) He doesn't have enough thiamine probably as a result of chronic alcoholism.
D) His glial cells are overactive and are damaging healthy neurons.

E) B) and D)
F) C) and D)

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 The two basic kinds of cells in the nervous system are _____.


A) neurons and glia
B) dendrites and axons
C) ribosomes and lysosomes
D) neurons and axons

E) C) and D)
F) A) and B)

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 When a neuron's membrane is at rest, the concentration gradient tends to move sodium ____ the cell and the electrical gradient tends to move it ____ the cell.


A) into; into
B) into; out of
C) out of; into
D) out of; out of

E) A) and D)
F) B) and D)

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 Neurons differ most strongly from other body cells in their ____.


A) temperature
B) shape
C) osmotic pressure
D) mitochondria

E) A) and B)
F) A) and D)

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 Bryson is having a cavity filled at the dentist and was given Novocain to prevent feeling any pain. Later, he explains to his roommate how the Novocain worked to stop the pain. What did he tell his roommate?

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Bryson told his roommate that Novocain w...

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 Professor Rhodus is lecturing about selective permeability of neurons. What would he tell the class?


A) All ions can only travel in one direction across the membrane.
B) All molecules must cross the membrane via a designated channel.
C) Only certain molecules can cross the membrane freely.
D) Only sodium and potassium ions can cross the membrane.

E) A) and C)
F) B) and C)

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 Marquitta is studying for a quiz and records in her notes that glucose is the main source of fuel for the nervous system and enters the brain via _____.


A) active transport
B) passive transport
C) gaps in the ventricles
D) gaps in the blood-brain barrier

E) All of the above
F) B) and C)

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 Ribosomes are the part of a cell that ____.


A) performs metabolic activities
B) breaks down harmful chemicals
C) transports proteins
D) synthesizes new proteins

E) A) and B)
F) None of the above

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 Professor Case studies how drugs of abuse change the amount of chemical that neurons release from the presynaptic terminal into the ______.


A) dendritic terminal
B) junction between neurons
C) afferent space
D) nucleus

E) A) and D)
F) B) and C)

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 When a membrane is at rest, what attracts potassium ions to the inside of the cell?


A) An electrical gradient
B) A concentration gradient
C) Both an electrical gradient and a concentration gradient
D) Neither an electrical gradient nor a concentration gradient

E) B) and D)
F) A) and D)

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A

 Describe how the brain transports essential chemicals.

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The brain has several transport mechanis...

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 Molecules that can cross the blood-brain barrier are usually ____.


A) large, uncharged molecules, such as lactose
B) large, charged molecules
C) neurotransmitters, such as dopamine
D) molecules that can dissolve in the fats of the capillary walls

E) All of the above
F) B) and C)

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 Pok is in the lab and is measuring the resting potential of neurons. Approximately what should she measure as the resting potential?


A) -65 millivolts
B) 0 millivolts
C) 70 millivolts
D) -70 millivolts

E) None of the above
F) B) and D)

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 Andrew was exposed to the chicken pox virus as a child. What happened to that virus after it crossed the blood-brain barrier and entered Andrew's brain?


A) Andrew's natural killer cells were able to quickly destroy it.
B) The glia in his brain engulfed the virus and then natural killer cells destroyed them both.
C) Nothing happened since the chicken pox virus cannot cross the blood-brain barrier.
D) Nothing happened at first, but the virus remained there and caused negative effects for Andrew as he got older.

E) A) and B)
F) A) and C)

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 Professor Nuno explained to her class that glucose is so important to the brain because ______.


A) neurons and glial cells can only metabolize glucose.
B) glial cells can only breakdown glucose into energy that the neurons can use.
C) glucose is unique and can cross the blood-brain barrier to be used by neurons.
D) all other forms of energy are used up by the body and don't make it to the brain.

E) All of the above
F) A) and D)

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 Professor Lopez studies the specialized _________ in the eye that detect light.


A) motor neurons
B) sensory neurons
C) glial cells
D) interneurons

E) B) and C)
F) A) and C)

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B

 What occurs when depolarization is less than the cell's threshold?


A) Sodium is prevented from crossing the membrane.
B) Potassium is prevented from crossing the membrane.
C) Sodium crosses the membrane only slightly more than usual.
D) The cell will still produce an action potential.

E) A) and B)
F) A) and C)

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C

 When a neuron's membrane is at rest, the concentration gradient tends to move potassium ____ the cell and the electrical gradient tends to move it ____ the cell.


A) into; into
B) into; out of
C) out of; into
D) out of; out of

E) A) and B)
F) A) and C)

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 A membrane produces an action potential whenever the potential across it reaches what level?


A) the resting potential
B) -90 mV
C) the threshold of excitation
D) the refractory period

E) All of the above
F) C) and D)

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